Adrafinil vs Provigil

Adrafinil vs Provigil are psychostimulant drugs that have long been used to treat medical conditions like narcolepsy. Idiopathic hypersomnia and obstructive sleep apnea, hence the need for comparison of the action of Adrafinil vs Provigil. This is an important factor put into application by my many people who want to avoid sleep examples are night guards and workers taking night shift.


Functions and Working Mechanisms
Adrafinil vs Provigil act as psychostimulants by changing the form or certain neurotransmitters in the brain to promote wakefulness and both are available in oral form. Adrafinil is considered as a precursor to Provigil as a small percentage of it is converted to Provigil(Modafinil) in the liver while the rest is metabolized to modafinilic acid which in a way leads to metabolic stress hence undesirable, this also means that one requires a larger dose of Adrafinil to achieve the same effects for a smaller dose of modafinil, Adrafinil also improves memory in the elderly, in terms of pharmacodynamics, Provigil possess a greater specificity in its action and localization hence there is greater reduction in side effect as compared to Adrafinil in which through slow metabolism increases the quantity of modafinil in the body leading to severe stomach pains, hyperactive skin reactions and elevated action of liver enzymes.


Possible Side Effects
The adverse side effects isn’t a legally sanctioned drug and is therefore sold as an over the counter drug whereas Provigil is a prescription drug hence it is difficult for one to acquire it unless you are in diseased condition, Adrafinil is less potent than Provigil in the body hence higher doses are required to achieve maximum results.


Bottom Lines
The above factors comparison of Adrafinil vs Provigil make Provigil the most efficient drug to used as it has a lot of advantages.

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