There a number of different ingredients being used for various medications, drugs, and supplements designed to treat overweight or obesity – in other words, to reduce your weight. However, with such large number of different brands on the market, a lot of people will certainly get confused in choosing the right one for them. One of the tricks is actually by observing the key ingredients being used in the products. These ingredients often have been or have not been scientifically proven to provide weight-loss effects. Some of the popular ingredients are Orlistat and Phentermine. These two are chemical substances that are widely used as both drugs and supplements for weight-loss. What are the differences? Which one is best? Read on to find out!
Orlistat, also known as tetrahydrolipstatin, is a drug designed to treat obesity. Marketed as a prescription drug under various brands in countries all around the world, it primarily functions to prevent the absorption of fats from the human diet by acting as an inhibitor of the lipase enzyme. As the effect, it also reduces your calorie intake. It is intended to be used in conjunction with a supervised reduced-calorie diet.
Orlistat is derived from lipstatin, which is a potent natural inhibitor to pancreatic lipases acquired from the Streptomyces toxytricini bacterium. Orlistat is chosen over lipstatin because it is simpler and more stable. Orlistat works by inhibiting gastric and pancreatic lipases so that the enzymes won’t be able to break down complex fat molecules from the food into the absorbable free fatty acids. Studies show that it is able to reduce weight up to 3 kilograms within a year. Side effects may include steatorrhea (oily, loose stools).
Phentermine, the short for phenyl- tertiary-butylamine, is psychostimulant drug similar to amphetamine. It primarily functions as an appetite suppressant. It is available in various brands and is approved worldwide, including by USA’s FDA. It works by affecting the neuron system, reducing the hunger perception so that consumers don’t easily get hungry.
Currently, it is being studied in combination with other medications for obesity. As it only reduces and suppresses your appetite, it neither directly prevents your body from absorbing fats nor helps to break down the accumulated fats of the body. Side effects may include headaches, rash, agitation, and hypertension.
Between Orlistat and Phentermine, we recommend you to choose Orlistat because it directly addresses the source of the problem, fats. It prevents your body from absorbing too much fat, as opposed to Phentermine that only reduces appetite. Nevertheless, you still need to control your food intake!